Journal Articles

Zekavat SM, Raghu VK, Trinder M, Ye Y, Koyama S, Honigberg MC, Yu Z, Pampana A, Urbut S, Haidermota S, O'Regan DP, Zhao H, Ellinor PT, Segrè AV, Elze T, Wiggs JL, Martone J, Adelman RA, Zebardast N, Del Priore L, Wang JC, Natarajan P

Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature. Circulation. 2022; 145(2):134-150

DOI: 10.1161/CIRCULATIONAHA.121.057709

Celebi ARC, Park EA, Verticchio Vercellin AC, Tsikata E, Lee R, Shieh E, Antar H, Freeman M, Zhang J, Que C, Simavli H, McClurkin M, Guo R, Elze T, de Boer JF, Chen TC

Structure-Function Mapping Using a Three-Dimensional Neuroretinal Rim Parameter Derived From Spectral Domain Optical Coherence Tomography Volume Scans. Transl Vis Sci Technol. 2021; 10(6):28

DOI: 10.1167/tvst.10.6.28

Li Y, Hall NE, Pershing S, Hyman L, Haller JA, Lee AY, Lee CS, Chiang M, Lum F, Miller JW, Lorch A, Elze T

Age, Gender, and Laterality of Retinal Vascular Occlusion: A Retrospective Study from the IRIS® Registry. Ophthalmol Retina. 2021;

DOI: 10.1016/j.oret.2021.05.004

Saeedi O, Boland MV, D'Acunto L, Swamy R, Hegde V, Gupta S, Venjara A, Tsai J, Myers JS, Wellik SR, DeMoraes G, Pasquale LR, Shen LQ, Li Y, Elze T

Development and Comparison of Machine Learning Algorithms to Determine Visual Field Progression. Transl Vis Sci Technol. 2021; 10(7):27

DOI: 10.1167/tvst.10.7.27

Choi EY, Wong RCS, Thein T, Pasquale LR, Shen LQ, Wang M, Li D, Jin Q, Wang H, Baniasadi N, Boland MV, Yousefi S, Wellik SR, De Moraes CG, Myers JS, Bex PJ, Elze T

The Effect of Ametropia on Glaucomatous Visual Field Loss. J Clin Med. 2021; 10(13)

DOI: 10.3390/jcm10132796

Anchouche S, Hall N, Bal S, Dana R, Elze T, Miller JW, Lorch AC, Yin J

Chemical and thermal ocular burns in the United States: An IRIS registry analysis. Ocul Surf. 2021; 21:345-347

DOI: 10.1016/j.jtos.2021.03.008

Susanna FN, Melchior B, Paula JS, Boland MV, Myers JS, Wellik SR, Elze T, Pasquale LR, Shen LQ, Ritch R, Susanna R, Hood DC, Liebmann JM, De Moraes CG

Variability and Power to Detect Progression of Different Visual Field Patterns. Ophthalmol Glaucoma. 2021; 4(6):617-623

DOI: 10.1016/j.ogla.2021.04.004

Yang SA, Mitchell W, Hall N, Elze T, Lorch AC, Miller JW, Zebardast N

Trends and Usage Patterns of Minimally Invasive Glaucoma Surgery in the United States: IRIS® Registry Analysis 2013-2018. Ophthalmol Glaucoma. 2021; 4(6):558-568

DOI: 10.1016/j.ogla.2021.03.012

Li Y, Mitchell W, Elze T, Zebardast N

Association Between Diabetes, Diabetic Retinopathy, and Glaucoma. Curr Diab Rep. 2021; 21(10):38

DOI: 10.1007/s11892-021-01404-5

Rauscher FG, Wang M, Francke M, Wirkner K, Tönjes A, Engel C, Thiery J, Stenvinkel P, Stumvoll M, Loeffler M, Elze T, Ebert T

Renal function and lipid metabolism are major predictors of circumpapillary retinal nerve fiber layer thickness-the LIFE-Adult Study. BMC Med. 2021; 19(1):202

DOI: 10.1186/s12916-021-02064-8

Zebardast N, Sekimitsu S, Wang J, Elze T, Gharahkhani P, Cole BS, Lin MM, Segrè AV, Wiggs JL

Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank. Ophthalmology. 2021; 128(9):1300-1311

DOI: 10.1016/j.ophtha.2021.03.007

Moon JY, Garg I, Cui Y, Katz R, Zhu Y, Le R, Lu Y, Lu ES, Ludwig CA, Elze T, Wu DM, Eliott D, Miller JW, Kim LA, Husain D, Vavvas DG, Miller JB

Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia. Br J Ophthalmol. 2021;

DOI: 10.1136/bjophthalmol-2021-319540

Doshi H, Solli E, Elze T, Pasquale LR, Wall M, Kupersmith MJ

Unsupervised Machine Learning Identifies Quantifiable Patterns of Visual Field Loss in Idiopathic Intracranial Hypertension. Transl Vis Sci Technol. 2021; 10(9):37

DOI: 10.1167/tvst.10.9.37

Huang X, Sun J, Majoor J, Vermeer KA, Lemij H, Elze T, Wang M, Boland MV, Pasquale LR, Mohammadzadeh V, Nouri-Mahdavi K, Johnson C, Yousefi S

Estimating the Severity of Visual Field Damage From Retinal Nerve Fiber Layer Thickness Measurements With Artificial Intelligence. Transl Vis Sci Technol. 2021; 10(9):16

DOI: 10.1167/tvst.10.9.16

Yang SA, Mitchell WG, Hall N, Elze T, Miller JW, Lorch AC, Zebardast N

Usage Patterns of Minimally Invasive Glaucoma Surgery (MIGS) Differ by Glaucoma Type: IRIS Registry Analysis 2013-2018. Ophthalmic Epidemiol. 2021; :1-9

DOI: 10.1080/09286586.2021.1955391

Shuldiner SR, Boland MV, Ramulu PY, De Moraes CG, Elze T, Myers J, Pasquale L, Wellik S, Yohannan J

Predicting eyes at risk for rapid glaucoma progression based on an initial visual field test using machine learning. PLoS One. 2021; 16(4):e0249856

DOI: 10.1371/journal.pone.0249856

Choi EY, Li D, Fan Y, Pasquale LR, Shen LQ, Boland MV, Ramulu P, Yousefi S, De Moraes CG, Wellik SR, Myers JS, Bex PJ, Elze T, Wang M

Predicting Global Test-Retest Variability of Visual Fields in Glaucoma. Ophthalmol Glaucoma. 2021.

DOI: 10.1016/j.ogla.2020.12.001

Liu WW, McClurkin M, Tsikata E, Hui PC, Elze T, Celebi ARC, Khoueir Z, Lee R, Shieh E, Simavli H, Que C, Guo R, de Boer J, Chen TC

Three-dimensional Neuroretinal Rim Thickness and Visual Fields in Glaucoma: A Broken-stick Model. J Glaucoma. 2020 Oct; 29(10):952-963

DOI: 10.1097/IJG.0000000000001604

Yousefi S, Elze T, Pasquale LR, Saeedi O, Wang M, Shen LQ, Wellik SR, De Moraes CG, Myers JS, Boland MV

Monitoring Glaucomatous Functional Loss Using an Artificial Intelligence-Enabled Dashboard. Ophthalmology. 2020 Sep; 127(9):1170-1178

DOI: 10.1016/j.ophtha.2020.03.008

Wang M, Shen LQ, Pasquale LR, Wang H, Li D, Choi EY, Yousefi S, Bex PJ, Elze T

An Artificial Intelligence Approach to Assess Spatial Patterns of Retinal Nerve Fiber Layer Thickness Maps in Glaucoma. Transl Vis Sci Technol. 2020 Aug; 9(9):41

DOI: 10.1167/tvst.9.9.41

Winkler TW, Grassmann F, Brandl C, Kiel C, Günther F, Strunz T, Weidner L, Zimmermann ME, Korb CA, Poplawski A, Schuster AK, Müller-Nurasyid M, Peters A, Rauscher FG, Elze T, Horn K, Scholz M, Cañadas-Garre M, McKnight AJ, Quinn N, Hogg RE, Küchenhoff H, Heid IM, Stark KJ, Weber BHF

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease. BMC Med Genomics. 2020 Aug 26; 13(1):120

DOI: 10.1186/s12920-020-00760-7

Baniasadi N, Rauscher FG, Li D, Wang M, Choi EY, Wang H, Peschel T, Wirkner K, Kirsten T, Thiery J, Engel C, Loeffler M, Elze T

Norms of Interocular Circumpapillary Retinal Nerve Fiber Layer Thickness Differences at 768 Retinal Locations. Transl Vis Sci Technol. 2020 Aug 12; 9(9):23

DOI: 10.1167/tvst.9.9.23

Teng B, Li D, Choi EY, Shen LQ, Pasquale LR, Boland MV, Ramulu P, Wellik SR, De Moraes CG, Myers JS, Yousefi S, Nguyen T, Fan Y, Wang H, Bex PJ, Elze T, Wang M

Inter-Eye Association of Visual Field Defects in Glaucoma and Its Clinical Utility. ransl Vis Sci Technol. 2020; 9(12):22

DOI: 10.1167/tvst.9.12.22

Nikhil Bommakanti, Carlos G. De Moraes, Michael V. Boland, Jonathan S. Myers, Sarah R. Wellik, Tobias Elze, Louis R. Pasquale, Lucy Q. Shen, Robert Ritch and Jeffrey M. Liebmann

Baseline Age and Mean Deviation Affect the Rate of Glaucomatous Vision Loss. Journal of Glaucoma. 2020. 29: 31-38.

DOI: 10.1097/IJG.0000000000001401

Dian Li, Franziska G. Rauscher, Eun Young Choi, Mengyu Wang, Neda Baniasadi, Kerstin Wirkner, Toralf Kirsten, Joachim Thiery, Christoph Engel, Markus Loeffler and Tobias Elze

Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness. Ophthalmology. 2020. 127: 357-368.

DOI: 10.1016/j.ophtha.2019.09.019

Mengyu Wang, Jorryt Tichelaar, Louis R. Pasquale, Lucy Q. Shen, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes, Jonathan S. Myers, Pradeep Ramulu, MiYoung Kwon, Osamah J. Saeedi, Hui Wang, Neda Baniasadi, Dian Li, Peter J. Bex and Tobias Elze

Characterization of Central Visual Field Loss in End-stage Glaucoma by Unsupervised Artificial Intelligence. JAMA Ophthalmology. 2020. 138(2):190-198

DOI: 10.1001/jamaophthalmol.2019.5413

Mengyu Wang, Lucy Q. Shen, Louis R. Pasquale, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes, Jonathan S. Myers, Thao D. Nguyen, Robert Ritch, Pradeep Ramulu, Hui Wang, Jorryt Tichelaar, Dian Li, Peter J. Bex and Tobias Elze

Artificial Intelligence Classification of Central Visual Field Patterns in Glaucoma. Ophthalmology. 2020. 127: 731-738.

DOI: 10.1016/j.ophtha.2019.12.004

Eileen L. Mayro, Mengyu Wang, Tobias Elze and Louis R. Pasquale

The impact of artificial intelligence in the diagnosis and management of glaucoma. Eye, 2020. 34(1): p. 1-11.

DOI: 10.1038/s41433-019-0577-x

Mengyu Wang, Lucy Q. Shen, Louis R. Pasquale, Paul Petrakos, Sydney Formica, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes, Jonathan S. Myers, Osamah Saeedi, Hui Wang, Neda Baniasadi, Dian Li, Jorryt Tichelaar, Peter J. Bex and Tobias Elze

An Artificial Intelligence Approach to Detect Visual Field Progression in Glaucoma Based on Spatial Pattern Analysis. Investigative Opthalmology & Visual Science. 2019. 60: 365.

DOI: 10.1167/iovs.18-25568

David J. Smits, Tobias Elze, Haobing Wang and Louis R. Pasquale

Machine Learning in the Detection of the Glaucomatous Disc and Visual Field. Seminars in Ophthalmology. 2019. 34: 232-242.

DOI: 10.1080/08820538.2019.1620801

Osamah J. Saeedi, Tobias Elze, Loris D Acunto, Ramya Swamy, Vikram Hegde, Surabhi Gupta, Amin Venjara, Joby Tsai, Jonathan S. Myers, Sarah R. Wellik, Carlos Gustavo De Moraes, Louis R. Pasquale, Lucy Q. Shen and Michael V. Boland

Agreement and Predictors of Discordance of 6 Visual Field Progression Algorithms. Ophthalmology. 2019. 126: 822-828.

DOI: 10.1016/j.ophtha.2019.01.029

Mengyu Wang, Qingying Jin, Hui Wang, Dian Li, Neda Baniasadi and Tobias Elze

The Interrelationship between Refractive Error, Blood Vessel Anatomy, and Glaucomatous Visual Field Loss. Translational Vision Science & Technology. 2018. 7: 4.

DOI: 10.1167/tvst.7.1.4

Mengyu Wang, Qingying Jin, Hui Wang, Neda Baniasadi and Tobias Elze

Quantifying positional variation of retinal blood vessels in glaucoma. PLOS ONE. 2018. 13: e0193555.

DOI: 10.1371/journal.pone.0193555

Mengyu Wang, Yaohua Zhang, Wenjing Wu, Joshua A. Young, Kathryn M. Hatch, Roberto Pineda II, Tobias Elze and Yan Wang

Predicting Refractive Outcome of Small Incision Lenticule Extraction for Myopia Using Corneal Properties. Translational Vision Science & Technology. 2018. 7: 11.

DOI: 10.1167/tvst.7.5.11

Mengyu Wang, Louis R. Pasquale, Lucy Q. Shen, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes, Jonathan S. Myers, Hui Wang, Neda Baniasadi, Dian Li, Rafaella Nascimento E. Silva, Peter J. Bex and Tobias Elze

Reversal of Glaucoma Hemifield Test Results and Visual Field Features in Glaucoma. Ophthalmology. 2018. 125: 352-360.

DOI: 10.1016/j.ophtha.2017.09.021

Matthias M. Mauschitz, Pieter W. M. Bonnemaijer, Kersten Diers, Franziska G. Rauscher, Tobias Elze, Christoph Engel, et al

Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population. Ophthalmology. 2018. 125: 1526-1536.

DOI: 10.1016/j.ophtha.2018.03.026

Michael Dorr, Tobias Elze, Hui Wang, Zhong-Lin Lu, Peter J. Bex and Luis A. Lesmes

New Precision Metrics for Contrast Sensitivity Testing. EEE Journal of Biomedical and Health Informatics. 2018. 22: 919-925.

DOI: 10.1109/JBHI.2017.2708745

Mengyu Wang, Hui Wang, Louis R. Pasquale, Neda Baniasadi, Lucy Q. Shen, Peter J. Bex and Tobias Elze

Relationship Between Central Retinal Vessel Trunk Location and Visual Field Loss in Glaucoma. American Journal of Ophthalmology. 2017. 176: 53-60.

DOI: 10.1016/j.ajo.2017.01.001

Mengyu Wang, Lucy Q. Shen, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes, Jonathan S. Myers, Peter J. Bex and Tobias Elze

Impact of Natural Blind Spot Location on Perimetry. Scientific Reports. 2017. 7: 6143.

DOI: 10.1038/s41598-017-06580-7

Mengyu Wang, Tobias Elze, Dian Li, Neda Baniasadi, Kerstin Wirkner, Toralf Kirsten, Joachim Thiery, Markus Loeffler, Christoph Engel and Franziska G. Rauscher

Age, ocular magnification, and circumpapillary retinal nerve fiber layer thickness. ournal of Biomedical Optics. 2017. 22: 1.

DOI: 10.1117/1.JBO.22.12.121718

Tobias Elze, Neda Baniasadi, Qingying Jin and Hui Wang

Ametropia, retinal anatomy, and OCT abnormality patterns in glaucoma. 1. Impacts of refractive error and interartery angle. Journal of Biomedical Optics. 2017. 22: 1.

DOI: 10.1117/1.JBO.22.12.121713

Neda Baniasadi, Mengyu Wang, Hui Wang, Mufeed Mahd and Tobias Elze

Associations between Optic Nerve Head–Related Anatomical Parameters and Refractive Error over the Full Range of Glaucoma Severity. Translational Vision Science & Technology. 2017. 6: 9.

DOI: 10.1167/tvst.6.4.9

Neda Baniasadi, Mengyu Wang, Hui Wang, Qingying Jin and Tobias Elze

Ametropia, retinal anatomy, and OCT abnormality patterns in glaucoma. 2. Impacts of optic nerve head parameters. Journal of Biomedical Optics. 2017. 22: 1.

DOI: 10.1117/1.JBO.22.12.121714

Michael Dorr, Luis A. Lesmes, Tobias Elze, Hui Wang, Zhong-Lin Lu and Peter J. Bex

Evaluation of the precision of contrast sensitivity function assessment on a tablet device. Scientific Reports. 2017. 7: 46706.

DOI: 10.1038/srep46706

Sophie Cai, Tobias Elze, Peter J. Bex, Janey L. Wiggs, Louis R. Pasquale and Lucy Q. Shen

Clinical Correlates of Computationally Derived Visual Field Defect Archetypes in Patients from a Glaucoma Clinic. Current Eye Research. 2017. 42: 568-574.

DOI: 10.1080/02713683.2016.1205630

Tobias Elze, Christopher Taylor and Peter J. Bex

An evaluation of organic light emitting diode monitors for medical applications: Great timing, but luminance artifacts. Medical Physics. 2013. 40: 092701.

DOI: 10.1118/1.4818056

Tobias Elze, Louis R. Pasquale, Lucy Q. Shen, Teresa C. Chen, Janey L. Wiggs and Peter J. Bex

Patterns of functional vision loss in glaucoma determined with archetypal analysis. Journal of The Royal Society Interface. 2015. 12: 20141118.

DOI: 10.1098/rsif.2014.1118

Neda Baniasadi, Eleftherios I. Paschalis, Mahdi Haghzadeh, Pallavi Ojha, Tobias Elze, Mufeed Mahd and Teresa C. Chen

Patterns of Retinal Nerve Fiber Layer Loss in Different Subtypes of Open Angle Glaucoma Using Spectral Domain Optical Coherence Tomography. Journal of Glaucoma. 2016. 25: 865-872.

DOI: 10.1097/IJG.0000000000000534

Tobias Elze and Thomas G. Tanner

Liquid crystal display response time estimation for medical applications. Medical Physics. 2009. 36: 4984-4990.

DOI: 10.1118/1.3238154

Tobias Elze

Achieving precise display timing in visual neuroscience experiments. Journal of Neuroscience Methods. 2010. 191: 171-179.

DOI: 10.1016/j.jneumeth.2010.06.018

Tobias Elze

Misspecifications of Stimulus Presentation Durations in Experimental Psychology: A Systematic Review of the Psychophysics Literature. PLoS ONE. 2010. 5: e12792.

DOI: 10.1371/journal.pone.0012792

Rainer Stollhoff, Jürgen Jost, Tobias Elze and Ingo Kennerknecht

The Early Time Course of Compensatory Face Processing in Congenital Prosopagnosia. PLoS ONE. 2010. 5: e11482.

DOI: 10.1371/journal.pone.0011482

Tobias Elze, Chen Song, Rainer Stollhoff and Jürgen Jost

Chinese characters reveal impacts of prior experience on very early stages of perception. BMC Neuroscience. 2011. 12: 14.

DOI: 10.1186/1471-2202-12-14

Rainer Stollhoff, Jürgen Jost, Tobias Elze and Ingo Kennerknecht

Deficits in Long-Term Recognition Memory Reveal Dissociated Subtypes in Congenital Prosopagnosia. PLoS ONE. 2011. 6: e15702.

DOI: 10.1371/journal.pone.0015702

Rainer Stollhoff, Ingo Kennerknecht, Tobias Elze and Jürgen Jost

A computational model of dysfunctional facial encoding in congenital prosopagnosia. Neural Networks. 2011. 24: 652-664.

DOI: 10.1016/j.neunet.2011.03.006

Tobias Elze and Thomas G. Tanner

Temporal Properties of Liquid Crystal Displays: Implications for Vision Science Experiments. PLoS ONE. 2012. 7: e44048.

DOI: 10.1371/journal.pone.0044048

Stephan Poppe, Philipp Benner and Tobias Elze

A predictive approach to nonparametric inference for adaptive sequential sampling of psychophysical experiments. ournal of Mathematical Psychology. 2012. 56: 179-195.

DOI: 10.1016/j.jmp.2012.04.002

Latest News

Postdoctoral opening in computational genetics for eye diseases in 2023 Summer

New course partly supported by NIH P30: artificial intelligence in medicine

Postdoc Yan Luo joined our lab

Postdoc Yu Tian joined our lab

ARVO 2022 Annual Meeting: Travel Grant recipients