Contact Information

Email: nazlee_zebardast at

Nazlee Zebardast, MD, MS

Director of Glaucoma Imaging, Massachusetts Eye and Ear

Assistant Professor of Ophthalmology, Harvard Medical School


Harvard Catalyst Profile
Mass. Eye and Ear Profile


Nazlee Zebardast, MD is focused on developing machine learning based tools for disease detection, aiding clinicians in assessing for disease progression and eventually optimizing patient-related outcomes. Currently, in collaboration with researchers at Ocular Genomics Institute and Massachusetts General Hospital she is using statistical genetics and machine learning methods for glaucoma genetic risk prediction. Specifically, her research focuses on imaging genetics with aim to 1) develop a polygenic risk score for open angle glaucoma and construct deep learning models for glaucoma genetic risk prediction using fundus imaging and 2) define structural and longitudinal endophenotypes using machine learning methods that are closely aligned with disease subtype and progression and identify novel genetic markers for disease. This work could lay the foundation for optimized machine learning based screening tests built on fundus images and/or genetic risk profiling.

In addition to this work, Dr Zebardast has an established track record in global health and epidemiology research. She is currently working with a number of large datasets including NHANES, IFACE, SEE, UK Biobank, IRIS registry, Medicare and NEISS to answer important clinical questions. Specifically, she is currently exploring the extensive IRIS registry to better understand the current use of MIGS in the US and delineate which patients may most benefit from these procedures and using Medicare claims data to identify sociodemographic predictors of outcomes, healthcare utilization and cost among older adults with glaucoma.


  1. 2013


    Yale School of Medicine
  2. 2008


    Tissue Engineering, University of Toronto
  3. 2007

    BASc, with honors

    Engineering Science Biomedical Track, University of Toronto

Professional Experience

  1. 2018
    Glaucoma, Wilmer Eye Institute, Johns Hopkins University
  2. 2017
    Ophthalmology, Wilmer Eye Institute, Johns Hopkins University
  3. 2014
    Transitional Year Internship
    Yale New Haven Hospital

Awards / Grants

  • 2017
    Paul S. Lietman Global Travel Fellowship
  • 2016
    American Glaucoma Society Bernard Schwartz Memorial Award for best poster or paper presentation
  • 2015 and 2016
    Wilmer Mitchell Prize for best research by a Wilmer resident
  • 2014 and 2015
    Wilmer Research Grant Award